An integrated acoustic and dielectrophoretic particle manipulation in a microfluidic device for particle wash and separation fabricated by mechanical machining
نویسندگان
چکیده
منابع مشابه
An integrated acoustic and dielectrophoretic particle manipulation in a microfluidic device for particle wash and separation fabricated by mechanical machining.
In this study, acoustophoresis and dielectrophoresis are utilized in an integrated manner to combine the two different operations on a single polydimethylsiloxane (PDMS) chip in sequential manner, namely, particle wash (buffer exchange) and particle separation. In the washing step, particles are washed with buffer solution with low conductivity for dielectrophoretic based separation to avoid th...
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Integrating different steps on a chip for cell manipulations and sample preparation is of foremost importance to fully take advantage of microfluidic possibilities, and therefore make tests faster, cheaper and more accurate. We demonstrated particle manipulation in an integrated microfluidic device by applying hydrodynamic, electroosmotic (EO), electrophoretic (EP), and dielectrophoretic (DEP) ...
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This report discusses two aspects of the development of a high-throughput separation technique aimed at separating cells based on phenotypic differences in membrane composition using dielectrophoresis (DEP): automated particle characterization and electrodeless DEP separations. First we discuss an automated technique to measure cellular dielectrophoretic mobility as a function of frequency. Sec...
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To study acoustic microfluidic particle manipulation, a microfluidic channel was designed in AutoCAD and fabricated in a silicon wafer using potassium hydroxide etching and other cleanroom techniques. The first channel created was destructively tested and its fabrication techniques characterized; future channel development is outlined.
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Ultrasonic and dielectrophoretic particle manipulation have been studied for particle trajectory modification and particle trapping in microfluidic channels. We report an approach that combines dielectrophoresis (DEP) and ultrasonic fields to trap and concentrate particles and cells in an aqueous suspension. By simultaneously applying electric and ultrasonic fields to the sample, the favorable ...
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ژورنال
عنوان ژورنال: Biomicrofluidics
سال: 2016
ISSN: 1932-1058
DOI: 10.1063/1.4940431